![]() ![]() Now, one substantial piece of evidence has been added to the time-lapse equation in publication of a large RCT from ten Nordic IVF centres involving 776 patients - all of whom had at least two good quality blastocysts available at randomisation.(1) Thereafter, two randomised groups proceeded to single blastocyst transfer, the one selected according to morphology alone and the other according to findings from a commercially available time-lapse model. In explaining its reasoning, the HFEA notes ‘there is conflicting evidence from randomised controlled trials (RCTs) to show that it is effective at improving the chances of having a baby for most fertility patients’. ![]() ESHRE, however, in its forthcoming guideline on the use of add-ons in ART will still include time-lapse (as a ‘selective’ add-on), while the HFEA’s traffic-light rating of add-ons gives it a cautionary amber light. Although the assessment of embryo quality from time-lapse monitoring is recognised as an ‘add-on’ in IVF, its use in many laboratories – especially in Europe – has become routine over the past decade. ![]()
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